ubiquitinatedproteins

由 A Brik 著作 · 2023 — In this review, we will present the key synthetic strategies and their applications for the preparation of various ubiquitinated proteins. Furthermore, the use ...

由 KN Swatek 著作 · 2016 · 被引用 1614 次 — Protein ubiquitination is a dynamic multifaceted post-translational modification involved in nearly all aspects of eukaryotic biology.

由 J Callis 著作 · 2014 · 被引用 365 次 — The protein ubiquitin is a covalent modifier of proteins, including itself. The ubiquitin system encompasses the enzymes required for ...

Ubiquitination is a reversible process until proteins become polyubiquitinated and are destined for degradation. The modulation of protein expression is ...

Ubiquitinated Protein. Ubiquitinated proteins are then, most commonly, targeted to the 26S proteasome, a large multisubunit cytoplasmic protease that degrades ...

由 M Sun 著作 · 2022 · 被引用 8 次 — Ubiquitination is a versatile post-translational modification (PTM), which regulates diverse fundamental features of protein substrates, ...

由 HJ Guo 著作 · 2022 · 被引用 16 次 — One of the best understood functions of ubiquitination is protein degradation. This pathway targets proteins to the proteasome, which degrades ...

The ubiquitin protein itself consists of 76 amino acids and has a molecular mass of about 8.6 kDa. Key features include its C-terminal tail and the 7 lysine ...